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Abstract
Errors during speeded response tasks are typically immediately followed by a large component in the event-related potential, the error-related negativity; various lines of research have suggested that this component is primarily generated by the anterior cingulate cortex. This error-related activity has generated a high level of interest and investigation by cognitive neuroscientists because of the importance of online action monitoring for theories of cognitive regulation. A subsequent component, the error positivity, has remained more elusive to date. In this review we will discuss some of the extensive research which has suggested that these components are related to performance monitoring, and, should performance be compromised, dynamically adjusting control processes. Furthermore, evidence from patients with mental illnesses, including schizophrenia and obsessive-compulsive disorder, suggests that such illnesses might be understood as resulting in part from disturbances in this action monitoring function.
References
Section:
| 1. | Rabbitt, PMA Errors and error-correction in choice-response tasks. J Exp Psychol 1966; 71: 264–272. Google Scholar, Crossref, Medline |
| 2. | Rabbitt, PMA, Vyas, S. Processing a display even after you make a response to it: How perceptual errors can be corrected. Quart J Exp Psychol Hum Exp Psychol 1981; 33A: 223–239. Google Scholar, Crossref |
| 3. | Laming, D. Choice reaction performance following an error. Acta Psychol 1979; 43: 199–224. Google Scholar, Crossref, ISI |
| 4. | Falkenstein, M, Hohnsbein, J, Hoormann, J, Blanke, L. Effects of crossmodal divided attention on late ERP components: II. Error processing in choice reaction tasks. Electroencephalogr Clin Neurophysiol 1991; 78: 447–455. Google Scholar, Crossref, Medline |
| 5. | Gehring, WJ, Goss, B, Coles, MGH, Meyer, DE, Donchin, E. A neural system for error detection and compensation. Psychol Sci 1993; 4: 385–390. Google Scholar, SAGE Journals, ISI |
| 6. | Dehaene, S, Posner, MI, Tucker, DM Localization of a neural system for error detection and compensation. Psychol Sci 1994; 5: 303–305. Google Scholar, SAGE Journals, ISI |
| 7. | van Veen, V, Carter, CS The timing of action-monitoring processes in the anterior cingulate cortex. J Cognit Neurosci 2002; 14: 593–602. Google Scholar, Crossref, Medline, ISI |
| 8. | Brázdil, M, Roman, R, Falkenstein, M, Daniel, P, Jurák, P, Rektor, I. Error processing—evidence from intracerebral ERP recordings. Exp Brain Res 2002; 146: 460–466. Google Scholar, Crossref, Medline, ISI |
| 9. | Carter, CS, Braver, TS, Barch, DM, Botvinick, MM, Noll, DC, Cohen, JD Anterior cingulate cortex, error detection, and the online monitoring of performance. Science 1998; 280: 747–749. Google Scholar, Crossref, Medline, ISI |
| 10. | Kerns, JG, Cohen, JD, MacDonald, AW, Cho, RY, Stenger, VA, Carter, CS Anterior cingulate conflict monitoring and adjustments in control. Science 2004; 303: 1023–1026. Google Scholar, Crossref, Medline, ISI |
| 11. | Debener, S, Ullsperger, M, Siegel, M, Fiehler, K, von Cramon, DY, Engel, AK Trial-by-trial coupling of concurrent electroencephalogram and functional magnetic resonance imaging identifies the dynamics of performance monitoring. J Neurosci 2005; 25: 11730–11737. Google Scholar, Crossref, Medline, ISI |
| 12. | Kiehl, KA, Liddle, PF, Hopfinger, JB Error processing and the rostral anterior cingulate: An event-related fMRI study. Psychophysiology 2000; 33: 282–294. Google Scholar |
| 13. | Herrmann, MJ, Rommler, J, Ehlis, A-C, Heidrich, A, Fallgatter, AJ Source localization (LORETA) of the error-related-negativity (ERN/Ne) and positivity (Pe). Cognit Brain Res 2004; 20: 294–299. Google Scholar, Crossref, Medline |
| 14. | Falkenstein, M, Hoormann, J, Christ, S, Hohnsbein, J. ERP components on reaction errors and their functional significance: A tutorial. Biol Psychol 2000; 51: 87–107. Google Scholar, Crossref, Medline, ISI |
| 15. | Hajcak, G, Moser, JS, Yeung, N, Simons, RF On the ERN and the significance of errors. Psychophysiology 2005; 42: 151–160. Google Scholar, Crossref, Medline, ISI |
| 16. | Rodríguez-Fornells, A, Kurzbuch, AR, Münte, TF Time course of error detection and correction in humans: Neurophysiological evidence. J Neurosci 2002; 22: 9990–9996. Google Scholar, Medline, ISI |
| 17. | Kopp, B, Rist, F, Mattler, U. N200 in the flanker task as a neurobehavioral tool for investigating executive control. Psychophysiology 1996; 33: 282–294. Google Scholar, Crossref, Medline, ISI |
| 18. | Scheffers, MK, Coles, MGH, Bernstein, P, Gehring, WJ, Donchin, E. Event-related brain potentials and error-related processing: An analysis of incorrect responses to go and no-go stimuli. Psychophysiology 1996; 33: 42–53. Google Scholar, Crossref, Medline, ISI |
| 19. | Garavan, H, Ross, TJ, Murphy, K, Roche, RAP, Stein, EA Dissociable executive functions in the dynamic control of behavior: Inhibition, error detection, and correction. NeuroImage 2002; 17: 1820–1829. Google Scholar, Crossref, Medline, ISI |
| 20. | Hajcak, G, McDonald, N, Simons, RF To err is autonomic: Error-related brain potentials, ANS activity, and post-error compensatory behavior. Psychophysiology 2003; 40: 895–903. Google Scholar, Crossref, Medline, ISI |
| 21. | Botvinick, MM, Braver, TS, Barch, DM, Carter, CS, Cohen, JD Conflict monitoring and cognitive control. Psychol Rev 2001; 108: 624–652. Google Scholar, Crossref, Medline, ISI |
| 22. | Botvinick, MM, Cohen, JD, Carter, CS Conflict monitoring and anterior cingulate cortex: An update. Trends Cognit Sci 2004; 8: 539–546. Google Scholar, Crossref, Medline, ISI |
| 23. | van Veen, V, Carter, CS The anterior cingulate as a conflict monitor: Fmri and ERP studies. Physiology Behav 2002; 77: 477–482. Google Scholar, Crossref, Medline, ISI |
| 24. | Nieuwenhuis, S, Yeung, N, van den Wildenberg, W, Ridderinkhof, KR Electrophysiological correlates of anterior cingulate function in a go/no-go task: Effects of response conflict and trial type frequency. Cognit Affect Behav Neurosci 2003; 3: 17–26. Google Scholar, Crossref, Medline, ISI |
| 25. | Jones, AD, Cho, RY, Nystrom, LE, Cohen, JD, Braver, TS A computational model of anterior cingulate function in speeded response tasks: Effects of frequency, sequence, and conflict. Cognit Affect Behav Neurosci 2003; 2: 300–317. Google Scholar, Crossref, ISI |
| 26. | Yeung, N, Botvinick, MM, Cohen, JD The neural basis of error detection: Conflict monitoring and the error-related negativity. Psychol Rev 2004; 111: 931–959. Google Scholar, Crossref, Medline, ISI |
| 27. | De Bruijn, ERA, Hulstijn, W, Verkes, RJ, Ruigt, GSF, Sabbe, BGC Drug-induced stimulation and suppression of action monitoring in healthy volunteers. Psychopharmacology 2004; 177: 151–160. Google Scholar, Crossref, Medline, ISI |
| 28. | Ridderinkhof, KR, de Vlugt, Y, Bramlage, A, Spaan, M, Elton, M, Snel, J, Band, GPH Alcohol consumption impairs detection of performance errors in mediofrontal cortex. Science 2002; 298: 2209–2211. Google Scholar, Crossref, Medline, ISI |
| 29. | Riba, J, Rodriguez-Fornells, A, Münte, TF, Barbanoj, MJ A neurophysiological study of the detrimental effects of alprazolam on human action monitoring. Cognit Brain Res 2005; 25: 554–565. Google Scholar, Crossref, Medline |
| 30. | Riba, J, Rodriguez-Fornells, A, Morte, A, Münte, TF, Barbanoj, MJ Noradrenergic stimulation enhances human action monitoring. J Neurosci 2005; 25: 4370–4374. Google Scholar, Crossref, Medline, ISI |
| 31. | Zirnheld, PJ, Carroll, CA, Kieffaber, PD, O'Donnell, BF, Shekhar, A, Hetrick, WP Haloperidol impairs learning and error-related negativity in humans. J Cognit Neurosci 2004; 16: 1098–1112. Google Scholar, Crossref, Medline, ISI |
| 32. | Holroyd, CB, Coles, MGH The neural basis of human error processing: Reinforcement learning, dopamine, and the error-related negativity. Psychol Rev 2002; 109: 679–709. Google Scholar, Crossref, Medline, ISI |
| 33. | Miltner, WHR, Braun, CH, Coles, MGH Event-related brain potentials following incorrect feedback in a time-estimation task: Evidence for a “generic” neural system for error detection. J Cognit Neurosci 1997; 9: 788–798. Google Scholar, Crossref, Medline, ISI |
| 34. | Gehring, WJ, Willoughby, AR The medial frontal cortex and the rapid processing of monetary gains and losses. Science 2002; 295: 2279–2282. Google Scholar, Crossref, Medline, ISI |
| 35. | Ito, S, Stuphorn, V, Brown, JW, Schall, JD Performance monitoring by the anterior cingulate cortex during saccade countermanding. Science 2003; 302: 120–122. Google Scholar, Crossref, Medline, ISI |
| 36. | van Veen, V, Holroyd, CB, Cohen, JD, Stenger, VA, Carter, CS Errors without conflict: Implications for performance monitoring theories of anterior cingulate cortex. Brain Cognition 2004; 56: 267–276. Google Scholar, Crossref, Medline, ISI |
| 37. | Nieuwenhuis, S, Slagter, HA, von Geusau, Alting NJ, Heslenfeld, DJ, Holroyd, CB Knowing good from bad: Differential activation of human cortical areas by positive and negative outcomes. Euro J Neurosci 2005; 21: 3161–3168. Google Scholar, Crossref, Medline, ISI |
| 38. | Nieuwenhuis, S, Ridderinkhof, KR, Blom, J, Band, GPH, Kok, A. Error-related brain potentials are differentially related to awareness of response errors: Evidence from an antisaccade task. Psychophysiology 2001; 38: 752–760. Google Scholar, Crossref, Medline, ISI |
| 39. | Hajcak, G, McDonald, N, Simons, RF Error-related psychophysiology and negative affect. Br Cogn 2004; 56: 189–197. Google Scholar, Crossref, Medline, ISI |
| 40. | Tieges, Z, Ridderinkhof, KR, Snel, J, Kok, A. Caffeine strengthens action monitoring: Evidence from the error-related negativity. Cogn Br Res 2004; 21: 87–93. Google Scholar, Crossref, Medline |
| 41. | Eriksen, BA, Eriksen, CW Effects of noise letters upon the identification of a target letter in a nonsearch task. Percept Psychophys 1974; 16: 143–149. Google Scholar, Crossref |
| 42. | Rist, F. Kopp B. An event-related brain potential substrate of disturbed response monitoring in paranoid schizophrenic patients. J Abnorm Psychol 1999; 108: 337–346. Google Scholar, Crossref, Medline, ISI |
| 43. | Alain, C, McNeely, HE, He, Y, Christensen, BK, West, R. Neurophysiological evidence of error-monitoring deficits in patients witn schizophrenia, Cereb Cortex 2002; 12: 840–846. Google Scholar, Crossref, Medline, ISI |
| 44. | Kerns, JG, Cohen, JD, MacDonald, AW, Johnson, MK, Stenger, VA, Aizenstein, H, Carter, CS Decreased conflict- and error-related activity in the anterior cingulate cortex in subjects with schizophrenia. Am J Psychiat 2005; 162: 1833–1839. Google Scholar, Crossref, Medline, ISI |
| 45. | Liotti, M, Pliszka, SR, Perez, R, Kothmann, D, Woldorff, MG Abnormal brain activity related to performance monitoring and error detection in children with ADHD. Cortex 2005; 41: 377–388. Google Scholar, Crossref, Medline, ISI |
| 46. | Schachar, RJ, Chen, S, Logan, GD, Ornstein, TJ, Crosbie, J, Ickowicz, A, Pakulak, A. Evidence for an error monitoring deficit in attention deficit hyperactivity disorder. J Abnorm Child Psychol 2004; 32: 285–293. Google Scholar, Crossref, Medline, ISI |
| 47. | Gehring, WJ, Himle, J, Nisenson, LG Action-monitoring dysfunction in obsessive-compulsive disorder. Psychol Sci 2000; 11: 1–6. Google Scholar, SAGE Journals, ISI |
| 48. | Hajcak, G, Simons, RF Error-related brain activity in obsessive-compulsive undergraduates. Psychiatry Research 2002; 110: 63–72. Google Scholar, Crossref, Medline, ISI |
| 49. | Johannes, S, Wieringa, BM, Nager, W, Müller-Vahl, KR, Dengler, R, Münte, TF. Excessive action monitoring in Tourette syndrome. J Neurol 2002; 249: 961–966. Google Scholar, Crossref, Medline, ISI |
| 50. | Ursu, S, Jones, M, Shear, MK, Stenger, VA, Carter, CS. Overactive action monitoring in obsessive-compulsive disorder: Evidence from functional MRI. Psychol Sci 2003; 14: 291–388. Google Scholar, SAGE Journals, ISI |
