Necropsy protocol for newborn mice
Abstract
Abstract
Neonatal mortality is high in laboratory mouse breeding, and causes are poorly understood. Post-mortem analysis of pups is an often overlooked source of information and insight. We present a necropsy protocol for neonatal mice designed for easy practical application by animal technicians.
Résumé
La mortalité néonatale liée à la reproduction des souris est élevée en laboratoire et les causes en sont mal comprises. L’analyse post-mortem des petits est une source d’informations souvent négligée. Nous présentons un protocole d’autopsie des souriceaux nouveaux-nés conçu pour faciliter une application pratique par des techniciens animaliers.
Abstrakt
Die neonatale Sterblichkeit ist in der Labormauszucht hoch, und ihre Ursachen sind nur unzureichend bekannt. Die Post-Mortem-Analyse von Jungmäusen ist eine häufig ignorierte Quelle für Informationen und Erkenntnisse. Wir stellen ein Nekropsie-Protokoll für neonatale Mäuse vor, das zur einfachen, praktischen Anwendung für Tierpfleger vorgesehen ist.
Resumen
La mortalidad neonatal es alta entre los roedores de laboratorio y las causas de ello no acaban de comprenderse. El análisis post mortem de las crías suele ser una técnica desestimada y que sin embargo aporta bastante información y datos. Presentamos un protocolo de necropsia para roedores neonatales diseñada para aplicarse de forma sencilla por parte de técnicos de animales.
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References
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Article first published online: January 10, 2021
Issue published: August 2021
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PubMed: 33423607
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