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First published online April 25, 2011

Central Pattern Generators of the Mammalian Spinal Cord

Abstract

Neuronal networks within the spinal cord of mammals are responsible for generating various rhythmic movements, such as walking, running, swimming, and scratching. The ability to generate multiple rhythmic movements highlights the complexity and flexibility of the mammalian spinal circuitry. The present review describes features of some rhythmic motor behaviors generated by the mammalian spinal cord and discusses how the spinal circuitry is able to produce different rhythmic movements with their own sets of goals and demands.

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References

Armstrong DM. 1988. The supraspinal control of mammalian locomotion. J Physiol 405:1–37.
Arshavsky YI, Kots YM, Orlovsky GN, Rodionov IM, Shik ML. 1965. Biophysics of complex systems and mathematical models. Investigation of the biomechanics of running by the dog. Biophysics 10:737–46.
Barbeau H, Rossignol S. 1987. Recovery of locomotion after chronic spinalization in the adult cat. Brain Res 412:84–95.
Barbeau H, Rossignol S. 1990. The effects of serotonergic drugs on the locomotor pattern and on cutaneous reflexes of the adult chronic spinal cat. Brain Res 514:55–67.
Barriere G, Frigon A, Leblond H, Provencher J, Rossignol S. 2010. Dual spinal lesion paradigm in the cat: evolution of the kinematic locomotor pattern. J Neurophysiol 104:1119–33.
Berg RW, Alaburda A, Hounsgaard J. 2007. Balanced inhibition and excitation drive spike activity in spinal half-centers. Science 315:390–3.
Berkowitz A. 2007. Spinal interneurons that are selectively activated during fictive flexion reflex. J Neurosci 27:4634–41.
Berkowitz A. 2008. Physiology and morphology of shared and specialized spinal interneurons for locomotion and scratching. J Neurophysiol 99:2887–901.
Brownstone RM, Wilson JM. 2008. Strategies for delineating spinal locomotor rhythm-generating networks and the possible role of Hb9 interneurones in rhythmogenesis. Brain Res Rev 57:64–76.
Brustein E, Rossignol S. 1998. Recovery of locomotion after ventral and ventrolateral spinal lesions in the cat: I. Deficits and adaptive mechanisms. J Neurophysiol 80:1245–67.
Cazalets JR, Sqalli-Houssaini Y, Clarac F. 1992. Activation of the central pattern generators for locomotion by serotonin and excitatory amino acids in neonatal rat. J Physiol 455:187–204.
Cazalets JR, Sqalli-Houssaini Y, Clarac F. 1994. GABAergic inactivation of the central pattern generators for locomotion in isolated neonatal rat spinal cord. J Physiol 474:173–81.
Conway BA, Hultborn H, Kiehn O. 1987. Proprioceptive input resets central locomotor rhythm in the spinal cat. Exp Brain Res 68:643–56.
Cote MP, Gossard JP. 2003. Task-dependent presynaptic inhibition. J Neurosci 23:1886–93.
Courtine G, Gerasimenko Y, van den Brand R, Yew A, Musienko P, Zhong H and others. 2009. Transformation of nonfunctional spinal circuits into functional states after the loss of brain input. Nat Neurosci 12:1333–42.
Cowley KC, Schmidt BJ. 1994. A comparison of motor patterns induced by N-methyl-D-aspartate, acetylcholine and serotonin in the in vitro neonatal rat spinal cord. Neurosci Lett 171:147–50.
Cowley KC, Schmidt BJ. 1995. Effects of inhibitory amino acid antagonists on reciprocal inhibitory interactions during rhythmic motor activity in the in vitro neonatal rat spinal cord. J Neurophysiol 74:1109–17.
Degtyarenko AM, Simon ES, Norden-Krichmar T, Burke RE. 1998. Modulation of oligosynaptic cutaneous and muscle afferent reflex pathways during fictive locomotion and scratching in the cat. J Neurophysiol 79:447–63.
Deliagina TG, Feldman AG, Gelfand IM, Orlovsky GN. 1975. On the role of central program and afferent inflow in the control of scratching movements in the cat. Brain Res 100:297–313.
Deliagina TG, Orlovsky GN. 1980. Activity of Ia inhibitory interneurons during fictitious scratch reflex in the cat. Brain Res 193:439–47.
Deliagina TG, Orlovsky GN, Perret C. 1981. Efferent activity during fictitious scratch reflex in the cat. J Neurophysiol 45:595–604.
Dietz V, Michel J. 2009. Human bipeds use quadrupedal coordination during locomotion. Ann N Y Acad Sci 1164:97–103.
Endo T, Kiehn O. 2008. Asymmetric operation of the locomotor central pattern generator in the neonatal mouse spinal cord. J Neurophysiol 100:3043–54.
Etlin A, Blivis D, Ben-Zwi M, Lev-Tov A. 2010. Long and short multifunicular projections of sacral neurons are activated by sensory input to produce locomotor activity in the absence of supraspinal control. J Neurosci 30:10324–36.
Feldman AG, Orlovsky GN. 1975. Activity of interneurons mediating reciprocal Ia inhibition during locomotion. Brain Res 84:181–94.
Frigon A. 2009. Reconfiguration of the spinal interneuronal network during locomotion in vertebrates. J Neurophysiol 101:2201–203.
Frigon A, Gossard JP. 2009. Asymmetric control of cycle period by the spinal locomotor rhythm generator in the adult cat. J Physiol 587:4617–28.
Frigon A, Gossard JP. 2010. Evidence for specialized rhythm-generating mechanisms in the adult mammalian spinal cord. J Neurosci 30:7061–71.
Frigon A, Rossignol S. 2006. Functional plasticity following spinal cord lesions. Prog Brain Res 157:231–60.
Frigon A, Sirois J, Gossard J-P. 2010. The effects of ankle and hip muscle afferent inputs on rhythm generation during fictive locomotion. J Neurophysiol 103:1591–605.
Geertsen SS, Stecina K, Meehan CF, Nielsen JB, Hultborn H. 2011. Reciprocal Ia inhibition contributes to motoneuronal hyperpolarisation during the inactive phase of locomotion and scratching in the cat. J Physiol 589(Pt 1):119–34.
Giuliani CA, Smith JL. 1985. Development and characteristics of airstepping in chronic spinal cats. J Neurosci 5:1276–82.
Gosgnach S, Lanuza GM, Butt SJ, Saueressig H, Zhang Y, Velasquez T and others. 2006. V1 spinal neurons regulate the speed of vertebrate locomotor outputs. Nature 440:215–9.
Grasso R, Ivanenko YP, Zago M, Molinari M, Scivoletto G, Castellano V and others. 2004. Distributed plasticity of locomotor pattern generators in spinal cord injured patients. Brain 127:1019–34.
Grillner S. 1981. Control of locomotion in bipeds, tetrapods, and fish. In: Brookhart JM, Mountcastle VB editors. Handbook of physiology: the nervous system II. Bethesda, MD: American Physiology Society. p 1179–236.
Grillner S, Dubuc R. 1988. Control of locomotion in vertebrates: spinal and supraspinal mechanisms. In: Waxman DG editor. Functional recovery in neurological disease. New York: Raven. p 425–53.
Grillner S, Georgopoulos AP, Jordan LM. 1997. Selection and initiation of motor behavior. In: Stein PSG, Grillner S, Selverston AI, Stuart DG, editors. Neurons, networks, and motor behavior. Cambridge, MA: MIT Press. p 3–19.
Grillner S, Halbertsma J, Nillsson J, Thorstensson A. 1979. The adaptation to speed in human locomotion. Brain Res 165:177–82.
Grillner S, Jessell TM. 2009. Measured motion: searching for simplicity in spinal locomotor networks. Curr Opin Neurobiol 19:572–86.
Grillner S, Zangger P. 1979. On the central generation of locomotion in the low spinal cat. Exp Brain Res 34:241–61.
Guertin P, Angel MJ, Perreault M-C, McCrea DA. 1995. Ankle extensor group I afferents excite extensors throughout the hindlimb during fictive locomotion in the cat. J Physiol 487:197–209.
Halbertsma JM. 1983. The stride cycle of the cat: the modelling of locomotion by computerized analysis of automatic recordings. Acta Physiol Scand Suppl 521:1–75.
Harvey PJ, Li X, Li Y, Bennett DJ. 2006. 5-HT2 receptor activation facilitates a persistent sodium current and repetitive firing in spinal motoneurons of rats with and without chronic spinal cord injury. J Neurophysiol 96:1158–70.
Hultborn H. 2006. Spinal reflexes, mechanisms and concepts: from Eccles to Lundberg and beyond. Prog Neurobiol 78:215–32.
Jiang W, Drew T. 1996. Effects of bilateral lesions of the dorsolateral funiculi and dorsal columns at the level of the low thoracic spinal cord on the control of locomotion in the adult cat: I. Treadmill walking. J Neurophysiol 76:849–66.
Jordan LM. 1998. Initiation of locomotion in mammals. Ann N Y Acad Sci 860:83–93.
Jordan LM, Liu J, Hedlund PB, Akay T, Pearson KG. 2008. Descending command systems for the initiation of locomotion in mammals. Brain Res Rev 57:183–91.
Juvin L, Simmers J, Morin D. 2005. Propriospinal circuitry underlying interlimb coordination in mammalian quadrupedal locomotion. J Neurosci 25:6025–35.
Juvin L, Simmers J, Morin D. 2007. Locomotor rhythmogenesis in the isolated rat spinal cord: a phase-coupled set of symmetrical flexion extension oscillators. J Physiol 583:115–28.
Kiehn O. 2011. Development and functional organization of spinal locomotor circuits. Curr Opin Neurobiol 21:100–9.
Kiehn O, Kjaerulff O. 1996. Spatiotemporal characteristics of 5-HT and dopamine-induced rhythmic hindlimb activity in the in vitro neonatal rat. J Neurophysiol 75:1472–82.
Klein DA, Patino A, Tresch MC. 2010. Flexibility of motor pattern generation across stimulation conditions by the neonatal rat spinal cord. J Neurophysiol 103:1580–90.
Klein DA, Tresch MC. 2010. Specificity of intramuscular activation during rhythms produced by spinal patterning systems in the in vitro neonatal rat with hindlimb attached preparation. J Neurophysiol 104:2158–68.
Koshland GF, Smith JL. 1989. Mutable and immutable features of paw-shake responses after hindlimb deafferentation in the cat. J Neurophysiol 62:162–73.
Krouchev N, Kalaska JF, Drew T. 2006. Sequential activation of muscle synergies during locomotion in the intact cat as revealed by cluster analysis and direct decomposition. J Neurophysiol 96:1991–2010.
Kuhta PC, Smith JL. 1990. Scratch responses in normal cats: hindlimb kinematics and muscle synergies. J Neurophysiol 64:1653–67.
Lafreniere-Roula M, McCrea DA. 2005. Deletions of rhythmic motoneuron activity during fictive locomotion and scratch provide clues to the organization of the mammalian central pattern generator. J Neurophysiol 94:1120–32.
Lev-Tov A, Etlin A, Blivis D. 2010. Sensory-induced activation of pattern generators in the absence of supraspinal control. Ann N Y Acad Sci 1198:54–62.
Li WC, Sautois B, Roberts A, Soffe SR. 2007. Reconfiguration of a vertebrate motor network: specific neuron recruitment and context-dependent synaptic plasticity. J Neurosci 27:12267–76.
Li X, Murray K, Harvey PJ, Ballou EW, Bennett DJ. 2007. Serotonin facilitates a persistent calcium current in motoneurons of rats with and without chronic spinal cord injury. J Neurophysiol 97:1236–46.
Marder E, Bucher D. 2001. Central pattern generators and the control of rhythmic movements. Curr Biol 11:R986–96.
McCrea DA, Rybak IA. 2008. Organization of mammalian locomotor rhythm and pattern generation. Brain Res Rev 57:134–46.
Murray KC, Nakae A, Stephens MJ, Rank M, D’Amico J, Harvey PJ and others. 2010. Recovery of motoneuron and locomotor function after spinal cord injury depends on constitutive activity in 5-HT2C receptors. Nat Med 16:694–700.
Musselman KE, Yang JF. 2007. Loading the limb during rhythmic leg movements lengthens the duration of both flexion and extension in human infants. J Neurophysiol 97:1247–57.
Nusbaum MP, Beenhakker MP. 2002. A small-systems approach to motor pattern generation. Nature 417:343–50.
Orsal D, Cabelguen J-M, Perret C. 1990. Interlimb coordination during fictive locomotion in the thalamic cat. Exp Brain Res 82:536–46.
Pearson KG, Misiaszek JE, Fouad K. 1998. Enhancement and resetting of locomotor activity by muscle afferents. Ann N Y Acad Sci 860:203–15.
Pearson KG, Rossignol S. 1991. Fictive motor patterns in chronic spinal cats. J Neurophysiol 66:1874–87.
Perreault M-C, Enriquez-Denton M, Hultborn H. 1999. Proprioceptive control of extensor activity during fictive scratching and weight support compared to fictive locomotion. J Neurosci 19:10966–76.
Perret C, Cabelguen J-M. 1976. Central and reflex participation in the timing of locomotor activations of a bifunctional muscle, the semi-tendinosus, in the cat. Brain Res 106:390–5.
Power KE, McCrea DA, Fedirchuk B. 2010. Intraspinally mediated state-dependent enhancement of motoneurone excitability during fictive scratch in the adult decerebrate cat. J Physiol 588:2839–57.
Quinlan KA, Kiehn O. 2007. Segmental, synaptic actions of commissural interneurons in the mouse spinal cord. J Neurosci 27:6521–30.
Rank MM, Li X, Bennett DJ, Gorassini MA. 2007. Role of endogenous release of norepinephrine in muscle spasms after chronic spinal cord injury. J Neurophysiol 97:3166–80.
Rossignol S, Barriere G, Alluin O, Frigon A. 2009. Re-expression of locomotor function after partial spinal cord injury. Physiology (Bethesda) 24:127–39.
Rossignol S, Dubuc R, Gossard JP. 2006. Dynamic sensorimotor interactions in locomotion. Physiol Rev 86:89–154.
Schmidt BJ, Jordan LM. 2000. The role of serotonin in reflex modulation and locomotor rhythm production in the mammalian spinal cord. Brain Res Bull 53:689–710.
Schomburg ED, Petersen N, Barajon I, Hultborn H. 1998. Flexor reflex afferents reset the step cycle during fictive locomotion in the cat. Exp Brain Res 122:339–50.
Sherrington CS. 1906. The integrative action of the nervous system. New Haven, CT: Yale University Press.
Sherrington CS. 1910. Notes on the scratch-reflex of the cat. Quart J Exp Physiol 3:213–20.
Smetana R, Juvin L, Dubuc R, Alford S. 2010. A parallel cholinergic brainstem pathway for enhancing locomotor drive. Nat Neurosci 13:731–8.
Smith JL, Hoy MG, Koshland GF, Phillips DM, Zernicke RF. 1985. Intralimb coordination of the paw-shake response: a novel mixed synergy. J Neurophysiol 54:1271–81.
Stecina K, Quevedo J, McCrea DA. 2005. Parallel reflex pathways from flexor muscle afferents evoking resetting and flexion enhancement during fictive locomotion and scratch in the cat. J Physiol 569:275–90.
Tresch MC, Jarc A. 2009. The case for and against muscle synergies. Curr Opin Neurobiol 19:601–7.
Vasudevan EV, Bastian AJ. 2010. Split-belt treadmill adaptation shows different functional networks for fast and slow human walking. J Neurophysiol 103:183–91.
Whelan PJ. 2010. Shining light into the black box of spinal locomotor networks. Philos Trans R Soc Lond B Biol Sci 365:2383–95.
Yakovenko S, McCrea DA, Stecina K, Prochazka A. 2005. Control of locomotor cycle durations. J Neurophysiol 94:1057–65.
Zangger P. 1981. The effect of 4-aminopyridine on the spinal locomotor rhythm induced by L-Dopa. Brain Res 215:211–23.
Zehr EP, Hundza SR, Vasudevan EV. 2009. The quadrupedal nature of human bipedal locomotion. Exerc Sport Sci Rev 37:102–8.

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Published In

Article first published online: April 25, 2011
Issue published: February 2012

Keywords

  1. central pattern generator
  2. locomotion
  3. scratch
  4. spinal cord
  5. spinal cord injury

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History

Published online: April 25, 2011
Issue published: February 2012
PubMed: 21518815

Authors

Affiliations

Alain Frigon
Department of Physiology and Biophysics, Université de Sherbrooke, Sherbrooke, Quebec, Canada

Notes

Alain Frigon, Department of Physiology and Biophysics, Université de Sherbrooke, 3001, 12e Avenue Nord, Sherbrooke, Quebec, J1H 5N4, Canada Email: [email protected]

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